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Foster, David A.

One or more keywords matched the following items that are connected to Foster, David A.

Item Type	Name
Academic Article	Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.
Academic Article	Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells.
Academic Article	Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells.
Academic Article	Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).
Academic Article	Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway.
Academic Article	Suppression of AKT phosphorylation restores rapamycin-based synthetic lethality in SMAD4-defective pancreatic cancer cells.
Academic Article	Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle.
Academic Article	High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
Academic Article	Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-?-dependent G1 cell cycle arrest.
Academic Article	Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric.
Academic Article	Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells.
Academic Article	Reciprocal regulation of AMP-activated protein kinase and phospholipase D.
Academic Article	Mutant ras elevates dependence on serum lipids and creates a synthetic lethality for rapamycin.
Academic Article	BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibition.
Academic Article	Rapamycin-induced G1 cell cycle arrest employs both TGF-? and Rb pathways.
Academic Article	Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.
Academic Article	The Enigma of Rapamycin Dosage.
Academic Article	Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells.
Academic Article	A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.
Academic Article	Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid.
Academic Article	Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine.
Academic Article	Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids.
Academic Article	Regulation of phosphatidic acid phosphohydrolase by epidermal growth factor. Reduced association with the EGF receptor followed by increased association with protein kinase Cepsilon.
Academic Article	Albumin promotes the progression of fibroblasts through late G1 into S-phase in the absence of growth factors.
Academic Article	Glutamine as an Essential Amino Acid for KRas-Driven Cancer Cells.
Academic Article	Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6.
Academic Article	Phospholipase D confers rapamycin resistance in human breast cancer cells.
Academic Article	The enigmatic protein kinase Cdelta: complex roles in cell proliferation and survival.
Academic Article	Targeting mTOR-mediated survival signals in anticancer therapeutic strategies.
Academic Article	Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells.
Academic Article	Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
Academic Article	Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells.
Academic Article	Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.
Academic Article	Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.
Academic Article	Alternative phospholipase D/mTOR survival signal in human breast cancer cells.
Academic Article	Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.
Academic Article	mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.
Academic Article	Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.
Academic Article	Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Academic Article	Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells.
Academic Article	Regulation of mTOR by phosphatidic acid?
Academic Article	Suppression of cell migration by protein kinase Cdelta.
Academic Article	The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.
Academic Article	Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.
Academic Article	Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
Academic Article	Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
Academic Article	Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras.
Academic Article	[Can defective TGF-Beta signaling be an Achilles heel in human cancer?].
Concept	Carrier Proteins
Concept	DNA-Binding Proteins
Concept	Membrane Proteins
Concept	Neoplasm Proteins
Concept	Nuclear Proteins
Concept	Protein Binding
Concept	Protein Kinase C
Concept	Protein Kinases
Concept	Protein Processing, Post-Translational
Concept	Protein-Tyrosine Kinases
Concept	Proteins
Concept	Proto-Oncogene Proteins
Concept	Recombinant Fusion Proteins
Concept	Oncogene Protein pp60(v-src)
Concept	Tumor Suppressor Protein p53
Concept	Retinoblastoma Protein
Concept	Proto-Oncogene Proteins c-myc
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Amyloid beta-Protein Precursor
Concept	Immediate-Early Proteins
Concept	ras Proteins
Concept	Cell Cycle Proteins
Concept	Ribosomal Protein S6 Kinases
Concept	Proto-Oncogene Proteins c-raf
Concept	Monomeric GTP-Binding Proteins
Concept	ral GTP-Binding Proteins
Concept	Mitogen-Activated Protein Kinases
Concept	Protein Transport
Concept	Tumor Suppressor Proteins
Concept	Intercellular Signaling Peptides and Proteins
Concept	Ubiquitin-Protein Ligases
Concept	Protein Kinase Inhibitors
Concept	Intracellular Signaling Peptides and Proteins
Concept	Adaptor Proteins, Signal Transducing
Concept	Proto-Oncogene Proteins c-akt
Concept	Glucose Transport Proteins, Facilitative
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Protein Kinase C-delta
Concept	Smad4 Protein
Concept	Amyloid Precursor Protein Secretases
Concept	Protein Phosphatase 2
Concept	AMP-Activated Protein Kinases
Concept	Protein Multimerization
Academic Article	Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin.
Academic Article	Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.

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GTP Binding Proteins